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Cardiology - Diseases & USMLE MCQs

10 clinical summaries in cardiology - each with pathophysiology, presentation, diagnosis, management, high-yield pearls, sample USMLE MCQs and an illustration from our medical library. Free to read, no login.

Acute Pericarditis

Acute Pericarditis

Inflammation of the pericardium causing sharp pleuritic chest pain, friction rub and diffuse ST elevation. Most often viral or idiopathic; risk of pericardial effusion and tamponade.

Reviewed 12 Jul 2026

Aortic Stenosis

Aortic Stenosis

Progressive calcific narrowing of the aortic valve causing left ventricular pressure overload, angina, syncope and heart failure. Leading valvular disease in the elderly.

Reviewed 2 Jun 2026

Atrial Fibrillation

Atrial Fibrillation

Most common sustained arrhythmia; irregular chaotic atrial activity causing irregularly irregular ventricular response with high stroke risk from atrial thrombus.

Reviewed 1 Jun 2026

Coronary Atherosclerosis and Stable Angina

Coronary Atherosclerosis and Stable Angina

Progressive lipid-driven arterial wall inflammation forming plaques that narrow coronary lumina and predispose to acute coronary syndromes.

Reviewed 12 May 2026

Deep Vein Thrombosis (DVT)

Deep Vein Thrombosis (DVT)

Thrombus in deep veins, usually of the lower limb. Risk = Virchow triad. Presents with unilateral leg swelling and pain; diagnosed by compression ultrasound and treated with anticoagulation.

Reviewed 23 May 2026

Dilated Cardiomyopathy

Dilated Cardiomyopathy

Left (or biventricular) chamber dilation with systolic dysfunction (LVEF <=40%) not solely due to ischaemia. Common causes: familial (TTN), viral myocarditis, alcohol, chemotherapy (anthracyclines) and peripartum.

Reviewed 18 Jun 2026

Heart Failure with Reduced Ejection Fraction (HFrEF)

Heart Failure with Reduced Ejection Fraction (HFrEF)

Systolic heart failure with LVEF <=40% due to ischaemic or non-ischaemic cardiomyopathy; four-pillar guideline-directed medical therapy dramatically improves outcomes.

Reviewed 2 Jul 2026

Hypertrophic Cardiomyopathy (HCM)

Hypertrophic Cardiomyopathy (HCM)

Autosomal-dominant sarcomeric disease causing asymmetric septal hypertrophy, dynamic LV outflow tract obstruction and increased sudden cardiac death risk in young athletes.

Reviewed 22 Jul 2026

Infective Endocarditis

Infective Endocarditis

Microbial infection of the endocardium (typically valves) producing vegetations, valvular destruction, systemic embolism and immune-complex disease.

Reviewed 12 Jul 2026

Rheumatic Heart Disease

Rheumatic Heart Disease

Chronic valvular sequela of acute rheumatic fever after group A streptococcal pharyngitis. Mitral stenosis is most typical. Preventable by early antibiotic treatment of strep throat.

Reviewed 15 Jun 2026

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